There are several notable new developments in chemical reagents manufacturers, spanning new technologies, emerging products, and market trends.

Key Developments
- New technology: Bipolar membrane electrodialysis for low-cost, green production of deuterated acids and bases. Production costs are ~1/5 of traditional routes, with near-zero emissions; 3-ton/year pilot achieved. Overturns the assumption that D2O dissociation is slower than H2O.
- New reagent: Difluoroallylating reagents (DFASs) enable selective installation of CF2 in C(sp3) contexts. Routes can be shorter and higher-yielding than traditional methods; also enable late-stage modification of peptides and proteins.
- Market growth: China’s chemical reagents manufacturers reached ~¥240 billion in 2024 and is projected to ¥260 billion in 2025, driven by high-purity and specialty needs.
- Green and intelligent trends: Shifts toward higher purity, higher selectivity, and green/sustainable reagents, along with automated and digitalized production/use for traceability and standardization.
- Industry/Product: Domestic players are expanding high-purity and specialty offerings, aiming to close the gap with international leaders; customized and application-oriented products are on the rise.

Quick Takeaways
- Deuterated reagents: Cheaper, greener production via bipolar membranes, with demonstrated pilot scale.
- Fluorinated reagents: New DFASs simplify and improve access to CF2-containing molecules, including in bioconjugation.
- Market: Continued growth with structural shift to high-end, specialty, and green products.